Peptidyl-Prolyl Cis-Trans Isomerase A

Preferred Label : Peptidyl-Prolyl Cis-Trans Isomerase A;

NCIt synonyms : Rotamase A; Cyclosporin A-Binding Protein; Cyclophilin A; Peptidyl-Prolyl Isomerase A; Peptidylprolyl Isomerase A; Epididymis Secretory Sperm Binding Protein Li 69p; EC 5.2.1.8; PPIase A; PPIA;

NCIt definition : Peptidyl-prolyl cis-trans isomerase A (165 aa, 18 kDa) is encoded by the human PPIA gene. This protein plays a role in cyclosporin-mediated immunosuppression, HIV virion assembly and protein folding.;

NCI Metathesaurus CUI : CL935910;

Details

Origin ID

C156929;

UMLS CUI

C4723744;

Automatic exact mappings (from CISMeF team)
- FKBP prolyl isomerase 2 [HGNC gene]
- FKBP prolyl isomerase family member 6 (inactive) [HGNC gene]
- FKBP prolyl isomerase family member 6 (inactive) [ORDO Gene]
- Peptidyl-prolyl isomerase a [OMIM gene]
- Peptidylprolyl isomerase (substance) [SNOMED CT concept]
- cyclophilin A [MeSH concept]
- cyclophilin a [MeSH Descriptor]
- cyclophilins [MeSH Descriptor]
- cyclophilins [MeSH concept]
- cyclosporin A binding [GO term]
- peptidylprolyl isomerase [MeSH Descriptor]
- peptidylprolyl isomerase [MeSH concept]
- peptidylprolyl isomerase A [HGNC gene]
- peptidylprolyl isomerase B [ORDO Gene]
OMIM relation
- Peptidyl-prolyl isomerase a [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
concept_is_in_subset
- NCIt COVID-19 Clinical Terminology [NCIt concept]
- NCIt COVID-19 Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Isomerase Gene [NCIt concept]
- PPIA Gene [NCIt concept]
gene_product_has_biochemical_function
- Chaperone [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- IL2RB Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Immunoregulation [NCIt concept]
- Protein Folding [NCIt concept]
- Virus Replication Cycle [NCIt concept]

Keyword's position in hierarchy(ies) :

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