Protein Phosphatase Slingshot Homolog 2

Preferred Label : Protein Phosphatase Slingshot Homolog 2;

NCIt synonyms : Slingshot Homolog 2; SSH-Like Protein 2; EC 3.1.3.48; EC 3.1.3.16; SSH-2L; hSSH-2L; SSH2;

NCIt definition : Protein phosphatase Slingshot homolog 2 (1423 aa, 158 kDa) is encoded by the human SSH2 gene. This protein plays a role in both the regulation of actin polymerization and the dephosphorylation of proteins.;

NCIt note : Protein phosphatase Slingshot homolog 2 has the potential to be a dual phosphoprotein phosphatase; however, protein tyrosine phosphatase activity has not been demonstrated. (UniProt);

Details

Origin ID

C114426;

UMLS CUI

C1999624;

OMIM relation
- Slingshot protein phosphatase 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- slingshot phosphatase 2, human [MeSH Supplementary Concept]
- slingshot phosphatase 2, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Esterase Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- Phosphatase Family Gene [NCIt concept]
- Protein Phosphatase Gene [NCIt concept]
- SSH2 Gene [NCIt concept]
gene_product_has_associated_anatomy
- Actin Filament [NCIt concept]
gene_product_has_biochemical_function
- Actin-Binding Protein [NCIt concept]
- Hydrolase [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Actin Cytoskeleton Regulation Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cytoskeletal Modeling [NCIt concept]
- Dephosphorylation [NCIt concept]
- Hydrolysis [NCIt concept]
- Protein Dephosphorylation [NCIt concept]

Keyword's position in hierarchy(ies) :

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