Methionine Synthase

Preferred Label : Methionine Synthase;

NCIt synonyms : 5-Methyltetrahydrofolate--Homocysteine Methyltransferase; MS; Cobalamin-Dependent Methionine Synthase; EC 2.1.1.13; Vitamin-B12 Dependent Methionine Synthase; 5-Methyltetrahydrofolate-Homocysteine Methyltransferase 1; MTR; 5-Methyltetrahydrofolate-Homocysteine Methyltransferase;

NCIt definition : Methionine synthase (1265 aa, 141 kDa) is encoded by the human MTR gene. This protein plays a role in the methylation of homocysteine.;

Details

Origin ID

C104949;

UMLS CUI

C3713294;

Automatic exact mappings (from CISMeF team)
- 5-Methyltetrahydrofolate homocysteine methyltransferase [LOINC component]
- 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase [MeSH Descriptor]
- 5-methyltetrahydrofolate-homocysteine methyltransferase [SNOMED Notion]
- 5-methyltetrahydrofolate-homocysteine methyltransferase [ORDO Gene]
- 5-methyltetrahydrofolate-homocysteine methyltransferase [HGNC gene]
- 5-methyltetrahydrofolate-homocysteine methyltransferase (substance) [SNOMED CT concept]
- 5-methyltetrahydrofolate-homocysteine s-methyltransferase [OMIM gene]
- Millisecond (qualifier value) [SNOMED CT concept]
- Mitral valve stenosis [ICD-11 Category]
- Multiple sclerosis [MedDRA Preferred Term]
- Multiple sclerosis [ICD-11 Category]
- Multiple sclerosis, susceptibility to [OMIM Phenotype]
- marginal sulcus [UBERON concept]
- mass spectrometry [MeSH Descriptor]
- multiple sclerosis [MedlinePlus Topic]
- upper extremity [MeSH Descriptor]
- vitamin B12-Dependent methionine synthase [MeSH concept]
OMIM relation
- 5-methyltetrahydrofolate-homocysteine s-methyltransferase [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- MTR protein, human [MeSH concept]
- MTR protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- MTR Gene [NCIt concept]
- Methyltransferase Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytosol [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Cysteine and Methionine Metabolism Pathway [NCIt concept]
- One Carbon Pool by Folate Pathway [NCIt concept]
- Selenoamino Acid Metabolism Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Amino Acid Biosynthesis [NCIt concept]
- Folic Acid Metabolic Process [NCIt concept]
- Methylation [NCIt concept]

Keyword's position in hierarchy(ies) :

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