E3 SUMO-Protein Ligase PIAS3

Preferred Label : E3 SUMO-Protein Ligase PIAS3;

NCIt synonyms : PIAS3; Protein Inhibitor of Activated STAT Protein 3; E3 SUMO-protein transferase PIAS3; Protein Inhibitor of Activated STAT3; Protein Inhibitor of Activated STAT3 Protein; EC 6.3.2.-, Formerly; EC 2.3.2.-;

NCIt definition : E3 SUMO-protein ligase PIAS3 (628 aa, 68 kDa) is encoded by the human PIAS3 gene. This protein plays a role in the regulation of protein sumoylation and in the inhibition of signal transducer and activator of transcription 3 transcription factor activity.;

Details

Origin ID

C30167;

UMLS CUI

C1436394;

OMIM relation
- Protein inhibitor of activated stat3 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- PIAS3 protein, human [MeSH concept]
- PIAS3 protein, human [MeSH Supplementary Concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Ligase Gene [NCIt concept]
- PIAS3 Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_has_structural_domain_or_motif
- Proline-Rich Domain [NCIt concept]
- Ring Finger Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Post-Translational Modification [NCIt concept]
- Signal Transduction [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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