Rho-Related GTP-Binding Protein RhoU

Preferred Label : Rho-Related GTP-Binding Protein RhoU;

NCIt synonyms : CDC42-Like GTPase; Rho GTPase-Like Protein ARHU; Wnt-1 Responsive Cdc42 Homolog; GTP-Binding Protein-Like 1; CDC42-Like GTPase 1; Wnt-1 Responsive Cdc42 Homolog 1; Ryu GTPase; WRCH-1; GTP-Binding Protein SB128; GTP-Binding Protein Like 1;

NCIt definition : Rho-related GTP-binding protein RhoU (258 aa, 28 kDa) is encoded by the human RHOU gene. This protein is involved in the regulation of cell migration.;

NCIt note : Rho-related GTP-binding protein RhoU has no detectable GTPase activity but does have high intrinsic guanine nucleotide exchange activity, which suggests it is constitutively GTP-bound. (UniProt);

Details

Origin ID

C114327;

UMLS CUI

C0968598;

Automatic exact mappings (from CISMeF team)
- Ras homolog gene family, member u [OMIM gene]
- ras homolog family member U [HGNC gene]
OMIM relation
- Ras homolog gene family, member u [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- RHOU protein, human [MeSH Supplementary Concept]
- RHOU protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- RHOU Gene [NCIt concept]
- Signaling Pathway Gene [NCIt concept]
gene_product_has_biochemical_function
- GTPase [NCIt concept]
gene_product_has_structural_domain_or_motif
- GTP Binding Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Mobility [NCIt concept]
- GTP Binding [NCIt concept]
- Hydrolysis [NCIt concept]
- Regulation of Cell Shape [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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