Tyrosyl-DNA Phosphodiesterase 1

Preferred Label : Tyrosyl-DNA Phosphodiesterase 1;

NCIt synonyms : EC 3.1.4.-; TDP1; Tyr-DNA Phosphodiesterase 1;

NCIt definition : Tyrosyl-DNA phosphodiesterase 1 (608 aa, 68 kDa) is encoded by the human TDP1 gene. This protein plays a role in single and double strand break repair of DNA.;

Details

Origin ID

C105096;

UMLS CUI

C3540645;

Automatic exact mappings (from CISMeF team)
- Tyrosyl-dna phosphodiesterase 1 [OMIM gene]
- tyrosyl-DNA phosphodiesterase 1 [ORDO Gene]
- tyrosyl-DNA phosphodiesterase 1 [HGNC gene]
OMIM relation
- Tyrosyl-dna phosphodiesterase 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- DNA Repair Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Esterase Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- TDP1 Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- DNA Exonuclease [NCIt concept]
- Hydrolase [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- DNA Binding [NCIt concept]
- DNA Repair [NCIt concept]
- Double Strand Break Repair [NCIt concept]
- Hydrolysis [NCIt concept]
- Single Strand Break Repair [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients