Ribonuclease 3

Preferred Label : Ribonuclease 3;

NCIt synonyms : Ribonuclease III; RNASE3L; Nuclear RNase III Drosha; EC 3.1.26.3; DROSHA; p241; RN3; RNase III; Putative Protein p241 which Interacts with Transcription Factor Sp1; Ribonuclease-III; Protein Drosha;

NCIt definition : Ribonuclease 3 (1374 aa, 159 kDa) is encoded by the human DROSHA gene. This protein is involved in microRNA biogenesis.;

Details

Origin ID

C29876;

UMLS CUI

C1869221;

Currated CISMeF NLP mapping
- Ribonuclease III (substance) [SNOMED CT concept]
- ribonuclease iii [SNOMED Notion]
False automatic mappings
- ribonuclease III [MeSH concept]
- ribonuclease iii [MeSH Descriptor]
OMIM relation
- Drosha ribonuclease III [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- DROSHA protein, human [MeSH Supplementary Concept]
- DROSHA protein, human [MeSH concept]
- Ribonuclease III (substance) [SNOMED CT concept]
- ribonuclease III [MeSH concept]
- ribonuclease iii [SNOMED Notion]
- ribonuclease iii [MeSH Descriptor]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- DROSHA Gene [NCIt concept]
- Endoribonuclease Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Esterase Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- Ribonuclease Gene [NCIt concept]
gene_product_has_biochemical_function
- Hydrolase [NCIt concept]
gene_product_has_chemical_classification
- RNase III Family Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Double-Stranded RNA Binding Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Hydrolysis [NCIt concept]
- MicroRNA Synthesis [NCIt concept]
- RNA Degradation [NCIt concept]
- RNA Interference [NCIt concept]
- RNA Processing [NCIt concept]

Keyword's position in hierarchy(ies) :

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