1-Phosphatidylinositol 4,5-Bisphosphate Phosphodiesterase Epsilon-1

Preferred Label : 1-Phosphatidylinositol 4,5-Bisphosphate Phosphodiesterase Epsilon-1;

NCIt synonyms : Phosphoinositide-Specific Phospholipase C Epsilon-1; EC 3.1.4.11; Phosphoinositide Phospholipase C-Epsilon-1; 1-Phosphatidylinositol-4,5-Bisphosphate Phosphodiesterase Epsilon-1; Phospholipase C-Epsilon-1; PLC-Epsilon-1; PLCE1;

NCIt definition : 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 (2302 aa, 259 kDa) is encoded by the human PLCE1 gene. This protein is involved in phospholipid metabolism, signaling, cell growth and cell survival.;

Details

Origin ID

C115069;

UMLS CUI

C1434268;

Automatic exact mappings (from CISMeF team)
- Phospholipase C, epsilon-1 [OMIM gene]
- phospholipase C epsilon 1 [ORDO Gene]
OMIM relation
- Phospholipase C, epsilon-1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- PLCE1 protein, human [MeSH concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Esterase Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- PLCE1 Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytosol [NCIt concept]
gene_product_has_biochemical_function
- Hydrolase [NCIt concept]
gene_product_has_structural_domain_or_motif
- C2 Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Calcium-Mediated Signaling Pathway [NCIt concept]
- Inositol Phosphate Metabolism Pathway [NCIt concept]
- Phosphatidylinositol Signaling System Pathway [NCIt concept]
- Phospholipase C-Epsilon Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Fatty Acid Metabolism [NCIt concept]
- Hydrolysis [NCIt concept]
- Phospholipid Metabolism [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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