Beta-Mannosidase

Preferred Label : Beta-Mannosidase;

NCIt synonyms : Mannosidase Beta; Mannanase; EC 3.2.1.25; MANBA; Mannase; Beta-Mannosidase A;

NCIt definition : Beta-mannosidase (879 aa, 101 kDa) is encoded by the human MANBA gene. This protein plays a role in the final exoglycosidase step for degradation of N-linked oligosaccharide moieties of glycoproteins.;

NCI Metathesaurus CUI : CL1374977;

Details

Origin ID

C203762;

UMLS CUI

C5197225;

OMIM relation
- Mannosidase, beta a, lysosomal [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- MANBA protein, human [MeSH Supplementary Concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- MANBA Gene [NCIt concept]
gene_product_has_associated_anatomy
- Azurophilic Granule [NCIt concept]
- Lumen of the Lysosome [NCIt concept]
- Plasma Membrane [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Glycoprotein Degradation Pathway [NCIt concept]
- Lysosome Assembly Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Carbohydrate Metabolic Process [NCIt concept]
- Catabolic Process [NCIt concept]
- Hydrolysis [NCIt concept]
- Post-Translational Modification [NCIt concept]

Keyword's position in hierarchy(ies) :

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