25-Hydroxycholesterol 7-Alpha-Hydroxylase

Preferred Label : 25-Hydroxycholesterol 7-Alpha-Hydroxylase;

NCIt synonyms : CYP7B1; Oxysterol 7-Alpha-Hydroxylase; EC 1.14.13.100; Oxysterol 7alpha-Hydroxylase; Cytochrome P450 7B1; Oxysterol 7-Alpha-Hydroxylase 1; Cytochrome P450 Family 7 Subfamily B Polypeptide 1;

NCIt definition : 25-hydroxycholesterol 7-alpha-hydroxylase (506 aa, 58 kDa) is encoded by the human CYP7B1 gene. This protein plays a role in the conversion of cholesterol into bile acids.;

Details

Origin ID

C114943;

UMLS CUI

C1432900;

Automatic exact mappings (from CISMeF team)
- 25-hydroxycholesterol 7alpha-hydroxylase activity [GO term]
- Cytochrome p450, family 7, subfamily b, polypeptide 1 [OMIM gene]
- cytochrome P450 family 7 subfamily B member 1 [ORDO Gene]
- oxysterol 7-alpha-hydroxylase [MeSH concept]
- oxysterol 7-alpha-hydroxylase [MeSH Supplementary Concept]
OMIM relation
- Cytochrome p450, family 7, subfamily b, polypeptide 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- CYP7B1 protein, human [MeSH Supplementary Concept]
- CYP7B1 protein, human [MeSH concept]
gene_encodes_gene_product
- CYP7B1 Gene [NCIt concept]
- Cytochrome P450 Family Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Oxidoreductase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Endoplasmic Reticulum [NCIt concept]
gene_product_has_chemical_classification
- Heme Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Bile Acid Biosynthesis Pathway [NCIt concept]
- Steroid Hormone Biosynthesis Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Detoxification [NCIt concept]
- Hydroxylation [NCIt concept]
- Intermediary Metabolic Process [NCIt concept]
- Lipid Metabolic Process [NCIt concept]
- Oxidation [NCIt concept]
- Oxidation/Reduction [NCIt concept]
- Steroid Metabolic Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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