Transaminase - CISMeF

Preferred Label : Transaminase;

NCIt synonyms : EC 2.6.1; Aminotransferase;

NCIt definition : Transaminases are a sub-subclass of mostly pyridoxal phosphate-dependent transferase enzymes that catalyze the transfer of an amino group from a donor (generally an amino acid) to an acceptor (generally a 2-keto acid). Mediating conversion of major intermediate metabolites and reversible transamination, Transaminases are often involved in cellular nitrogen metabolism, amino acid metabolism, gluconeogenesis and in the urea and tricarboxylic acid cycles.;

Details

Origin ID

C21489;

UMLS CUI

C0002594;

False automatic mappings
- Substance with aminotransferase mechanism of action (substance) [SNOMED CT concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
Validated automatic mappings to BTNT
- aspartate aminotransferase, cytoplasmic [MeSH Descriptor]
- aspartate aminotransferase, mitochondrial [MeSH Descriptor]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]

Keyword's position in hierarchy(ies) :

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