Protein Arginine N-Methyltransferase 5

Preferred Label : Protein Arginine N-Methyltransferase 5;

NCIt synonyms : Shk1 Kinase-Binding Protein 1 Homolog; SKB1Hs; 72 kDa ICln-Binding Protein; EC 2.1.1.320; EC 2.1.1.125; Jak-Binding Protein 1; HMT1 HnRNP Methyltransferase-Like 5; Protein Arginine Methyltransferase 5; SKB1 Homolog; Histone-Arginine N-Methyltransferase PRMT5;

NCIt definition : Protein arginine N-methyltransferase 5 (637 aa, 73 kDa) is encoded by the human PRMT5 gene. This protein is involved in the methylation of arginine.;

Details

Origin ID

C127857;

UMLS CUI

C4284027;

Automatic exact mappings (from CISMeF team)
- Protein arginine methyltransferase 5 [OMIM gene]
- protein arginine methyltransferase 5 [HGNC gene]
OMIM relation
- Protein arginine methyltransferase 5 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Methyltransferase Gene [NCIt concept]
- PRMT5 Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytoplasm [NCIt concept]
- Golgi Apparatus [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Methylation [NCIt concept]
- Protein Methylation [NCIt concept]
is_target
- Onametostat [NCIt concept]
- PRMT5 Inhibitor AMG 193 [NCIt concept]
- PRMT5 Inhibitor AUR-105 [NCIt concept]
- PRMT5 Inhibitor AZD3470 [NCIt concept]
- PRMT5 Inhibitor PRT811 [NCIt concept]
- PRMT5 Inhibitor SH3765 [NCIt concept]
- PRMT5 Inhibitor SKL27969 [NCIt concept]
- PRMT5 Inhibitor SYHX2001 [NCIt concept]
- PRMT5 Inhibitor TNG462 [NCIt concept]
- PRMT5 Inhibitor TNG908 [NCIt concept]
- PRMT5-MTA Inhibitor MRTX1719 [NCIt concept]
- Pemrametostat [NCIt concept]
- Protein Arginine Methyltransferase 5 Inhibitor PF-06939999 [NCIt concept]
- Protein Arginine Methyltransferase 5 Inhibitor PRT543 [NCIt concept]

Keyword's position in hierarchy(ies) :

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