Sphingosine-1-Phosphate Lyase 1

Preferred Label : Sphingosine-1-Phosphate Lyase 1;

NCIt synonyms : SP-Lyase 1; Sphingosine-1-Phosphate Aldolase; EC 4.1.2.27;

NCIt definition : Sphingosine-1-phosphate lyase 1 (568 aa, 64 kDa) is encoded by the human SGPL1 gene. This protein plays a role in apoptosis, the elevation of stress-induced ceramide production, and the metabolism of phosphorylated sphingoid bases.;

Details

Origin ID

C105033;

UMLS CUI

C3539829;

Automatic exact mappings (from CISMeF team)
- Sphingosine-1-phosphate lyase 1 [OMIM gene]
- sphingosine-1-phosphate lyase 1 [ORDO Gene]
- sphingosine-1-phosphate lyase 1 [HGNC gene]
OMIM relation
- Sphingosine-1-phosphate lyase 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Lyase Gene [NCIt concept]
- SGPL1 Gene [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]

Keyword's position in hierarchy(ies) :

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