Aldo-Keto Reductase Family 1 Member C1

Preferred Label : Aldo-Keto Reductase Family 1 Member C1;

NCIt synonyms : EC 1.3.1.20; EC 1.1.1.112; EC 1.1.1.149; Dihydrodiol Dehydrogenase 1; Aldo-Keto Reductase C; Type II 3-Alpha-Hydroxysteroid Dehydrogenase; Chlordecone Reductase Homolog HAKRC; Dihydrodiol Dehydrogenase Isoform DD1; Hepatic Dihydrodiol Dehydrogenase; High-Affinity Hepatic Bile Acid-Binding Protein; Trans-1,2-Dihydrobenzene-1,2-Diol Dehydrogenase; 20 Alpha-Hydroxysteroid Dehydrogenase; 20-Alpha-Hydroxysteroid Dehydrogenase; 20-Alpha-HSD; 2-Alpha-HSD; Dihydrodiol Dehydrogenase 1/2; Indanol Dehydrogenase; AKR1C1;

NCIt definition : Aldo-keto reductase family 1 member C1 (323 aa, 37 kDa) is encoded by the human AKR1C1 gene. This protein is involved in the conversion of progesterone to its inactive form and may have a role in the transport of bile.;

Détails

Origin ID

C105419;

UMLS CUI

C1721278;

Automatic exact mappings (from CISMeF team)
- 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity [GO term]
- 20-alpha-Hydroxysteroid dehydrogenase [MeSH concept]
- 20-alpha-hydroxysteroid dehydrogenase [MeSH Descriptor]
- 20-alpha-hydroxysteroid dehydrogenase (substance) [SNOMED CT concept]
- Aldo-keto reductase family 1, member 1 [OMIM gene]
- Aldo-keto reductase family 1, member c3 [OMIM gene]
- Estradiol 17beta-dehydrogenase (substance) [SNOMED CT concept]
- Indanol dehydrogenase (substance) [SNOMED CT concept]
- aldo-keto reductase family 1 member C1 [HGNC gene]
- estradiol 17-beta-dehydrogenase activity [GO term]
- indanol dehydrogenase [MeSH concept]
- indanol dehydrogenase [MeSH Supplementary Concept]
- indanol dehydrogenase [SNOMED Notion]
- trans-1,2-Dihydrobenzene-1,2-diol dehydrogenase (substance) [SNOMED CT concept]
- trans-1,2-dihydrobenzene-1,2-diol dehydrogenase [MeSH Supplementary Concept]
- trans-1,2-dihydrobenzene-1,2-diol dehydrogenase [MeSH concept]
- trans-1,2-dihydrobenzene-1,2-diol dehydrogenase [SNOMED Notion]
OMIM relation
- Aldo-keto reductase family 1, member 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- AKR1C1 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- AKR1C1 Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Oxidoreductase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytoplasm [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Metabolism of Xenobiotics by Cytochrome P450 Pathway [NCIt concept]
- Steroid Hormone Biosynthesis Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cholesterol Homeostasis [NCIt concept]
- Oxidation [NCIt concept]
- Oxidation/Reduction [NCIt concept]
- Steroid Metabolic Process [NCIt concept]
- Xenobiotic Metabolism [NCIt concept]

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