Uracil-DNA Glycosylase

Preferred Label : Uracil-DNA Glycosylase;

NCIt synonyms : UNG; UDG; EC 3.2.2.27; UDG1N; Uracil-DNA Glycosylase 2; Uracil-DNA Glycosylase Isoform 2; Uracil-DNA Glycosylase, Nuclear Isoform; UDG1A; UNG2;

NCIt definition : Uracil-DNA glycosylase (313 aa, 35 kDa) is encoded by the human UNG gene. This protein plays a role in DNA metabolism.;

NCIt note : Uracil-DNA glycosylase has 2 isoforms produced by alternative splicing. Isoform 1 is widely expressed and found in mitochondria. Isoform 2 is expressed in proliferating tissues and is found in the nucleus and is the canonical form according to UniProt.;

Details

Origin ID

C106308;

UMLS CUI

C4520806;

Automatic exact mappings (from CISMeF team)
- Cyclin o [OMIM gene]
- Lung [LOINC System]
- Lung [LOINC System]
- Uracil-DNA glycosidase [MeSH Descriptor]
- Uracil-dna glycosylase [OMIM gene]
- cyclin O [ORDO Gene]
- lung [MeSH Descriptor]
- uracil DNA glycosylase [ORDO Gene]
- uracil DNA glycosylase [HGNC gene]
OMIM relation
- Uracil-dna glycosylase [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- DNA Repair Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- UNG Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Base Excision Repair Pathway [NCIt concept]
- Primary Immunodeficiency Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Base Excision Repair [NCIt concept]
- DNA Repair [NCIt concept]
- Hydrolysis [NCIt concept]
- Immunoglobulin Gene Rearrangement Process [NCIt concept]

Keyword's position in hierarchy(ies) :

Main resources

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