Succimer - CISMeF

Preferred Label : Succimer;

NCIt synonyms : Meso 2, 3-Dimercaptosuccinic Acid; DMSA; Butanedioic Acid, 2,3-Dimercapto-, (2R,3S)-rel-;

NCIt definition : An orally active mercaptodicarboxylic acid, with heavy metal chelating activity. As a strong chelator, succimer is able to bind to heavy metals, such as lead, in the bloodstream, thereby forming a water-soluble complex that can be eliminated via urinary excretion. This prevents heavy metal poisoning. In addition, succimer is able to chelate the alpha particle emitter and radionuclide polonium Po 210 ((Po-210), thereby increasing its excretion and reducing the toxic effects of Po-210.;

UNII : DX1U2629QE;

InChIKey : ACTRVOBWPAIOHC-XIXRPRMCSA-N;

CAS number : 304-55-2;

Drug name : Chemet;

Chemical formula : C4H6O4S2;

ChEBI ID : CHEBI:63623;

Details

Origin ID

C61953;

UMLS CUI

C0012384;

Automatic exact mappings (from CISMeF team)
- Chemotherapy [LOINC component]
- W Chemotherapy [LOINC Challenge]
- drug therapy [MeSH Descriptor]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Product containing succimer (medicinal product) [SNOMED CT concept]
- Succimer (substance) [SNOMED CT concept]
- succimer [Substance BNPC]
- succimer [MeSH concept]
- succimer [MeSH Descriptor]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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