Lysosomal Protective Protein

Preferred Label : Lysosomal Protective Protein;

NCIt synonyms : Carboxypeptidase Y-Like Kininase; Beta-Galactosidase Protective Protein; Urinary Kininase; Carboxypeptidase-L; Cathepsin A; PPCA; CTSA; Carboxypeptidase C; Protective Protein for Beta-Galactosidase; EC 3.4.16.5; Protective Protein Cathepsin A; Carboxypeptidase L; Lysosomal Carboxypeptidase A;

NCIt definition : Lysosomal protective protein (480 aa, 54 kDa) is encoded by the human CTSA gene. This protein is involved in deamidase, esterase and carboxypeptidase activities in the lysosome.;

NCIt note : Lysosomal protective protein is translated as a preproprotein, which is proteolytically processed to generate two chains that comprise the heterodimeric active enzyme. (EntrezGene); Lysosomal protective protein is part of a heterotrimeric complex that includes beta-galactosidase and sialidase-1.;

Details

Origin ID

C200298;

OMIM relation
- Cathepsin a [OMIM gene]
gene_encodes_gene_product
- CTSA Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- Peptidase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Lysosome [NCIt concept]
gene_product_has_structural_domain_or_motif
- Protease Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Lysosome Assembly Pathway [NCIt concept]
- Renin-Angiotensin Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Autophagy [NCIt concept]
- Hydrolysis [NCIt concept]
- Proteolysis [NCIt concept]

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