5,6-Dihydroxyindole-2-Carboxylic Acid Oxidase

Preferred Label : 5,6-Dihydroxyindole-2-Carboxylic Acid Oxidase;

NCIt synonyms : Glycoprotein 75; Catalase B; Tyrosinase Related Protein-1; TYRP1; TRP-1; B-Protein; TYRP; EC 1.14.18.-; TRP; DHICA Oxidase; Tyrosinase-Related Protein-1; Melanoma Antigen gp75; Tyrosinase-Related Protein 1;

NCIt definition : 5,6-dihydroxyindole-2-carboxylic acid oxidase (537 aa, 61 kDa) is encoded by the human TYRP1 gene. This protein plays a role in melanin biosynthesis.;

Details

Origin ID

C18271;

UMLS CUI

C1455498;

Currated CISMeF NLP mapping
- B protein (neoplasm) [MeSH concept]
- B protein (neoplasm) [MeSH Supplementary Concept]
- protein B [MeSH concept]
- protein B (Pseudomonas putida) [MeSH concept]
- protein B (Pseudomonas putida) [MeSH Supplementary Concept]
- tyrosinase-related protein-1 [MeSH concept]
- tyrosinase-related protein-1 [MeSH Supplementary Concept]
OMIM relation
- Tyrosinase-related protein 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- TYRP1 protein, human [MeSH concept]
- TYRP1 protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
endogenous_product_related_to
- Recombinant Tyrosinase-Related Protein-1 [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Oxidoreductase Gene [NCIt concept]
- TYRP1 Gene [NCIt concept]
gene_product_has_associated_anatomy
- Melanocyte [NCIt concept]
gene_product_has_chemical_classification
- Glycoprotein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Melanogenesis Pathway [NCIt concept]
- p53 Effector Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Melanogenesis [NCIt concept]
- Oxidation [NCIt concept]
- Oxidation/Reduction [NCIt concept]
is_target
- Anti-TYRP1/CD3 T-cell Engager RO7293583 [NCIt concept]
- Flanvotumab [NCIt concept]
- Recombinant Vesicular Stomatitis Virus-expressing Interferon-beta and Tyrosinase Related Protein 1 [NCIt concept]
- TRP1(0RF3):1-9 Peptide [NCIt concept]

Keyword's position in hierarchy(ies) :

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