NCIt definition : A monoclonal antibody directed against the melanosomal membrane protein gp75 (or Tyrosinase-Related
Protein 1 (TRP1)) with potential immunostimulatory and antineoplastic activities.
Anti-gp75 monoclonal antibody IMC-20D7S targets and binds to gp75. This may lead to
the induction of cytotoxic T cell immune and antibody-mediated immune responses against
melanoma cells expressing gp75. gp75, a pigmentation-associated antigen, is expressed
in melanosomes of human melanocytes and melanomas.;
UNII : ZNV4738BS6;
CAS number : 1188277-05-5; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 1188277-05-5
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G-SRS /a ;
Semantic type(s)