Flanvotumab - CISMeF

Preferred Label : Flanvotumab;

NCIt synonyms : Anti-gp75 Monoclonal Antibody IMC-20D7S;

NCIt definition : A monoclonal antibody directed against the melanosomal membrane protein gp75 (or Tyrosinase-Related Protein 1 (TRP1)) with potential immunostimulatory and antineoplastic activities. Anti-gp75 monoclonal antibody IMC-20D7S targets and binds to gp75. This may lead to the induction of cytotoxic T cell immune and antibody-mediated immune responses against melanoma cells expressing gp75. gp75, a pigmentation-associated antigen, is expressed in melanosomes of human melanocytes and melanomas.;

UNII : ZNV4738BS6;

CAS number : 1188277-05-5;

Molecule name : IMC-20D7S;

NCI Metathesaurus CUI : CL421598;

Details

Origin ID

C91384;

UMLS CUI

C2984206;

Currated CISMeF NLP mapping
- Flanvotumab [SMS substance]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
chemical_or_drug_has_mechanism_of_action
- Antigen Binding [NCIt concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_target
- 5,6-Dihydroxyindole-2-Carboxylic Acid Oxidase [NCIt concept]

Keyword's position in hierarchy(ies) :

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