Aspartyl Peptidase

Preferred Label : Aspartyl Peptidase;

NCIt synonyms : Aspartic Protease; Aspartic Peptidase; Aspartyl Protease;

NCIt definition : Aspartyl Proteases (Aspartic Endopeptidases) have an acidic residue (aspartate) involved in the catalytic process, have a pH optimum below 5 and catalyze the cleavage of internal peptide bonds in a polypeptide or protein.;

Details

Origin ID

C28411;

UMLS CUI

C2717969;

Automatic exact mappings (from CISMeF team)
- aspartic acid proteases [MeSH concept]
- aspartic acid proteases [MeSH Descriptor]
Biochemical function of gene products
- Beta-Secretase 1 [NCIt concept]
- Beta-Secretase 2 [NCIt concept]
- Renin [NCIt concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- Peptidase Gene [NCIt concept]
gene_product_has_structural_domain_or_motif
- Protease Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Hydrolysis [NCIt concept]
is_chemical_classification_of_gene_product
- Presenilin-1 [NCIt concept]
- Presenilin-2 [NCIt concept]

Keyword's position in hierarchy(ies) :

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