Aspartate-tRNA Ligase, Mitochondrial

Preferred Label : Aspartate-tRNA Ligase, Mitochondrial;

NCIt synonyms : Aspartate--tRNA Ligase, Mitochondrial; DARS2; Aspartyl-tRNA Synthetase 2; EC 6.1.1.12; Aspartyl-tRNA Synthetase, Mitochondrial; AspRS; Aspartate tRNA Ligase 2, Mitochondrial; Aspartyl-tRNA Synthetase; Aspartyl-tRNA Synthetase 2, Mitochondrial;

NCIt definition : Aspartate-tRNA ligase, mitochondrial (645 aa, 74 kDa) is encoded by the human DARS2 gene. This protein plays a role in the aminoacylation of transfer RNA(Asp) in the mitochondrion.;

Details

Origin ID

C189077;

UMLS CUI

C3181631;

Automatic exact mappings (from CISMeF team)
- Aspartate-transfer ribonucleic acid ligase (substance) [SNOMED CT concept]
- Aspartyl-trna synthetase 1 [OMIM gene]
- Aspartyl-trna synthetase 2 [OMIM gene]
- aspartyl-tRNA synthetase 2, mitochondrial [HGNC gene]
- aspartyl-tRNA synthetase 2, mitochondrial [ORDO Gene]
OMIM relation
- Aspartyl-trna synthetase 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- DARS2 protein, human [MeSH Supplementary Concept]
- DARS2 protein, human [MeSH concept]
gene_encodes_gene_product
- DARS2 Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Ligase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Mitochondrion [NCIt concept]
gene_product_has_chemical_classification
- Aminoacyl-tRNA Ligase Family [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Aminoacyl-tRNA Biosynthesis Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- RNA Processing [NCIt concept]
- Translational Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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