D-3-Phosphoglycerate Dehydrogenase

Preferred Label : D-3-Phosphoglycerate Dehydrogenase;

NCIt synonyms : 3-Phosphoglycerate Dehydrogenase; EC 1.1.1.95; 3-PGDH; PHGDH;

NCIt related terms : PGDH;

NCIt definition : D-3-phosphoglycerate dehydrogenase (533 aa, 57 kDa) is encoded by the human PHGDH gene. This protein plays a role in the serine biosynthesis pathway.;

Alternative definition : CDISC: An antigen encoded by the PHGDH gene and is involved in the serine biosynthesis pathway. It can be considered as an autoantigen and is commonly associated with autoimmune liver diseases.;

Details

Origin ID

C99476;

UMLS CUI

C4048261;

OMIM relation
- Phosphoglycerate dehydrogenase [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
concept_is_in_subset
- CDISC SDTM Binding Agent for Immunogenicity Tests Terminology [NCIt concept]
- CDISC SDTM Terminology [NCIt concept]
- Clinical Data Interchange Standards Consortium Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Oxidoreductase Gene [NCIt concept]
- PHGDH Gene [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Glycine, Serine and Threonine Metabolism Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Amino Acid Biosynthesis [NCIt concept]
- Nervous System Development [NCIt concept]
- Oxidation [NCIt concept]
- Oxidation/Reduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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