Cytosolic Phospholipase A2

Preferred Label : Cytosolic Phospholipase A2;

NCIt synonyms : Cytosolic Phospholipase-A2G4A; PLA2G4; Phosphatidylcholine 2-Acylhydrolase; Phospholipase A2 Group IVA; Phospholipase A2 IVA; PLA2G4A; Lysophospholipase; Calcium-Dependent Cytosolic Phospholipase A2 IVA; Phospholipase A2; cPLA2-Alpha; CPLA2; Cytosolic Phospholipase A2G4A;

NCIt definition : Cytosolic phospholipase A2 (749 aa, 85 kDa) is encoded by the human PLA2G4A gene. This protein is involved in arachidonic acid metabolism.;

NCIt note : Cytosolic phospholipase A2 has phospholipase (EC 3.1.1.4) and lysophospholipase (EC 3.1.1.5) activities. (UniProt);

Details

Origin ID

C38589;

UMLS CUI

C0912034;

Automatic exact mappings (from CISMeF team)
- Carboxyl-ester lipase [OMIM gene]
- Phospholipase a2, group iva [OMIM gene]
- group II phospholipases A2 [MeSH Descriptor]
- group III phospholipases A2 [MeSH Descriptor]
- group x phospholipases a2 [MeSH Descriptor]
- lysophospholipase A [MeSH concept]
- phospholipase A2 group IVA [ORDO Gene]
- phospholipase A2 group IVA [HGNC gene]
- phospholipases A [MeSH Descriptor]
Currated CISMeF NLP mapping
- phospholipases A2, cytosolic [MeSH concept]
- phospholipases a2, cytosolic [MeSH Descriptor]
OMIM relation
- Phospholipase a2, group iva [OMIM gene]
See also inter- (CISMeF)
- Lysophospholipase (substance) [SNOMED CT concept]
- Phospholipase A>2< (substance) [SNOMED CT concept]
- group IVA phospholipase A2 [MeSH concept]
- group iv phospholipases a2 [MeSH Descriptor]
- lysophospholipase [MeSH Descriptor]
- lysophospholipase [MeSH concept]
- lysophospholipase [SNOMED Notion]
- phospholipase a2 [SNOMED Notion]
- phospholipases A2 [MeSH concept]
- phospholipases a2 [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- PLA2G4A protein, human [MeSH Supplementary Concept]
- PLA2G4A protein, human [MeSH concept]
- phospholipases A2, cytosolic [MeSH concept]
- phospholipases a2, cytosolic [MeSH Descriptor]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Esterase Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- PLA2G4A Gene [NCIt concept]
gene_product_has_biochemical_function
- Cytosolic Phospholipase A2 Group IV [NCIt concept]
- Hydrolase [NCIt concept]
gene_product_has_structural_domain_or_motif
- C2 Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Arachidonic Acid Metabolism Pathway [NCIt concept]
- Aspirin Inhibition of Platelet Activation Pathway [NCIt concept]
- Eicosanoid Metabolism Pathway [NCIt concept]
- Ether Lipid Metabolism Pathway [NCIt concept]
- Fc Epsilon Receptor I Signaling Pathway BioCarta [NCIt concept]
- Fc Epsilon Receptor I Signaling Pathway KEGG [NCIt concept]
- Fc Gamma Receptor-Mediated Phagocytosis Pathway [NCIt concept]
- Fc-Epsilon Receptor I Signaling Pathway PID [NCIt concept]
- Glycerophospholipid Metabolism Pathway [NCIt concept]
- Gonadotropin-Releasing Hormone Signaling Pathway [NCIt concept]
- Linoleic Acid Metabolism Pathway [NCIt concept]
- Long-Term Depression Pathway [NCIt concept]
- MAPK Signaling Pathway [NCIt concept]
- PDGFR-beta Signaling Pathway [NCIt concept]
- Prostaglandin and Leukotriene Metabolism Pathway [NCIt concept]
- VEGF Signaling Pathway [NCIt concept]
- Vascular Smooth Muscle Contraction Pathway [NCIt concept]
- alpha-Linolenic Acid Metabolism Pathway [NCIt concept]
- p38 MAPK Signaling Pathway BioCarta [NCIt concept]
- p38-alpha and p38-beta Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Hydrolysis [NCIt concept]
- Inflammatory Response [NCIt concept]
- Lipid Metabolic Process [NCIt concept]
- Signal Transduction [NCIt concept]

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