group III phospholipases A2

Preferred Label : group III phospholipases A2;

MeSH definition : A subcategory of secreted phospholipases A2 with specificity for PHOSPHATIDYLETHANOLAMINES and PHOSPHATIDYLCHOLINE. It occurs as a component of VENOMS and as a mammalian secretory phospholipase A2. The creation of this group is based upon similarities in the structural determinants of the enzymes including a long amino-terminal domain, a conserved group III-specific domain, and a long carboxyl-terminal domain.;

MeSH synonym : group iii secretory phospholipase a2; phospholipase a2 iii; phospholipase a2-iii; phospholipases a2, group iii;

Registry Number MeSH : EC 3.1.1.4;

MeSH annotation : /antag: coordinate with PHOSPHOLIPASE A2 INHIBITORS;

Is substance : O;

UNII : EC 3.1.1.4;

Details

Origin ID

D054520;

UMLS CUI

C1955949;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Record concept(s)
- group III phospholipases A2 [MeSH concept]
Related MeSH Supplementary Concept(s)
- PLA2G3 protein, human [MeSH Supplementary Concept]
- PLA2G3 protein, mouse [MeSH Supplementary Concept]
- Pla2g3 protein, rat [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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