group x phospholipases a2

Preferred Label : group x phospholipases a2;

MeSH definition : A secreted phospholipase A2 subtype that contains a interfacial-binding region with specificity for PHOSPHATIDYLCHOLINE. This enzyme group may play a role in eliciting ARACHIDONIC ACID release from intact cellular membranes and from LOW DENSITY LIPOPROTEINS. Members of this group bind specifically to PHOSPHOLIPASE A2 RECEPTORS.;

MeSH synonym : group x secretory phospholipase a(2); group x secretory phospholipase a2; gx spla(2); phospholipase a2, group x; phospholipases a2, group x; sPLA(2)-X; sPLA2-X;

Registry Number MeSH : EC 3.1.1.4;

MeSH annotation : /antag: coordinate with PHOSPHOLIPASE A2 INHIBITORS;

Is substance : O;

UNII : EC 3.1.1.4;

Details

Origin ID

D054509;

UMLS CUI

C1100642;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Cytosolic Phospholipase A2 [NCIt concept]
- PLA2G2A wt Allele [NCIt concept]
- Phospholipase A2 [NCIt concept]
- Phospholipase A2 Enzyme Family [NCIt concept]
- Phospholipase A>2< (substance) [SNOMED CT concept]
- Phospholipase a2, group X [OMIM gene]
- phospholipase A2 group X [HGNC gene]
- phospholipase a2 [SNOMED Notion]
Record concept(s)
- group X phospholipases A2 [MeSH concept]
Related MeSH Supplementary Concept(s)
- PLA2G10 protein, human [MeSH Supplementary Concept]
- PLA2G12B protein, human [MeSH Supplementary Concept]
- PLA2G12B protein, mouse [MeSH Supplementary Concept]
- Pla2g10 protein, mouse [MeSH Supplementary Concept]
- Pla2g10 protein, rat [MeSH Supplementary Concept]
- iPLA2-VIA protein, Drosophila [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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