group iv phospholipases a2

Preferred Label : group iv phospholipases a2;

MeSH definition : A cytosolic phospholipase A2 group that plays an important role in the release of free ARACHIDONIC ACID, which in turn is metabolized to PROSTAGLANDINS by the CYCLOOXYGENASE pathway and to LEUKOTRIENES by the 5-LIPOXYGENASE pathway.;

MeSH synonym : phospholipases a2, group iv; group iv cytosolic phospholipase a2; Phospholipase A2 IV; PLA2-IV; PLA(2)-IV;

MeSH hyponym : group IVF phospholipase A2; group IVE phospholipase A2; group IVB phospholipase A2; group IVC phospholipase A2; group IVD phospholipase A2; group IVA phospholipase A2; Phospholipase A2-beta; Phospholipase A2 beta; Phospholipase A2, Group IVB; Cytosolic Phospholipase A2 beta; Group IVB Phospholipases A2; Phospholipase A2, Group IVC; Cytosolic Phospholipase A2 gamma; cPLA2-gamma; cPLA2 gamma; Group IVC Phospholipases A2; Phospholipase A2-gamma; Phospholipase A2 gamma; Group IVE Phospholipases A2; Phospholipase A2, Group IVE; Cytosolic Phospholipase A2 epsilon; Phospholipase A2, Group IVF; Group IVF Phospholipases A2; Cytosolic Phospholipase A2 alpha; Phospholipase A2-alpha; Phospholipase A2 alpha; Phospholipase A(2)alpha; Phospholipase A2 Group IVA; cPLA2-alpha; cPLA2 alpha; Group IVA Phospholipases A2; Group IVD Phospholipases A2; Phospholipase A2, Group IVD; Cytosolic Phospholipase A2 delta;

MeSH Related Number : group IVF phospholipase A2; group IVB phospholipase A2; group IVA phospholipase A2; group IVE phospholipase A2; group IVC phospholipase A2; group IVD phospholipase A2; EC 3.1.1.4;

Registry Number MeSH : EC 3.1.1.4;

Related CAS MeSH : EC 3.1.1.4 (Group IVA phospholipase A2); EC 3.1.1.4 (Group IVE phospholipase A2); EC 3.1.1.4 (Group IVC phospholipase A2); EC 3.1.1.4 (Group IVD phospholipase A2); EC 3.1.1.4 (Group IVF phospholipase A2); EC 3.1.1.4 (Group IVB phospholipase A2);

MeSH annotation : /antag: coordinate with PHOSPHOLIPASE A2 INHIBITORS;

Is substance : O;

UNII : EC 3.1.1.4;

Details

Origin ID

D054513;

UMLS CUI

C1333201;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Currated CISMeF NLP mapping
- Cytosolic Phospholipase A2 Group IV [NCIt concept]
- Phospholipase a2, group iva [OMIM gene]
Indexing information
- 1-(3-(4-phenoxyphenoxy)-2-oxopropyl)indole-5-carboxylic acid [MeSH Supplementary Concept]
- 3-(3-methyl-1,2,4-oxadiazol-5-yl)-1-(3-(4-octylphenoxy)-2-oxopropyl)indole-5-carboxylic acid [MeSH Supplementary Concept]
- 3-(5-carboxypentanoyl)-1-(3-(4-octylphenoxy)-2-oxopropyl)indole-5-carboxylic acid [MeSH Supplementary Concept]
- 3-isobutanoyl-1-(2-oxo-3-(4-phenoxyphenoxy)propyl)indole-5-carboxylic acid [MeSH Supplementary Concept]
- 4-(3-(5-chloro-2-(2-(((2,6-dimethylbenzyl)sulfonyl)amino)ethyl)-1-(diphenylmethyl)-1H-indol-3-yl)propyl)benzoic acid [MeSH Supplementary Concept]
- 4-(hexadecyloxy)-3-(2-(hydroxyimino)-3-oxobutanamido)benzoic acid [MeSH Supplementary Concept]
- C2-di-ethyl-ceramide-1-phosphate [MeSH Supplementary Concept]
- N-((4-(biphenyl-2-ylmethoxy)-1-(2-(4-fluorobenzoyl)benzoyl)pyrrolidin-2-yl)methyl)-4-((2,4-dioxothiazolidin-5-ylidene)methyl)benzamide [MeSH Supplementary Concept]
- N-(-4-(N-(biphenyl-2-ylmethyl)-N-2-methylpropylamino)- 1-(2-(2,4-difluorobenzoyl)benzoyl)pyrrolidin- 2-yl)methyl-3-(4-(2,4-dioxothiazolidin-5-ylidenemethyl) phenyl)acrylamide [MeSH Supplementary Concept]
- PLA-695 [MeSH Supplementary Concept]
- efipladib [MeSH Supplementary Concept]
Record concept(s)
- group IV phospholipases A2 [MeSH concept]
- group IVA phospholipase A2 [MeSH concept]
- group IVB phospholipase A2 [MeSH concept]
- group IVC phospholipase A2 [MeSH concept]
- group IVD phospholipase A2 [MeSH concept]
- group IVE phospholipase A2 [MeSH concept]
- group IVF phospholipase A2 [MeSH concept]
Related MeSH Supplementary Concept(s)
- PLA2G4A protein, human [MeSH Supplementary Concept]
- PLA2G4B protein, human [MeSH Supplementary Concept]
- PLA2G4C protein, human [MeSH Supplementary Concept]
- PLA2G4D protein, human [MeSH Supplementary Concept]
- PLA2G4E protein, human [MeSH Supplementary Concept]
- PLA2G4F protein, human [MeSH Supplementary Concept]
- Pla2g4a protein, mouse [MeSH Supplementary Concept]
- Pla2g4a protein, rat [MeSH Supplementary Concept]
- Pla2g4b protein, mouse [MeSH Supplementary Concept]
- Pla2g4c protein, mouse [MeSH Supplementary Concept]
- Pla2g4d protein, mouse [MeSH Supplementary Concept]
- Pla2g4f protein, mouse [MeSH Supplementary Concept]
See also inter- (CISMeF)
- Cytosolic Phospholipase A2 [NCIt concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Cytosolic Phospholipase A2 Group IV [NCIt concept]

Keyword's position in hierarchy(ies) :

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