Guanylate-Binding Protein 2

Preferred Label : Guanylate-Binding Protein 2;

NCIt synonyms : huGBP-2; GTP-Binding Protein 2; Guanine Nucleotide-Binding Protein 2; GBP-2; GBP2; Guanylate Binding Protein 2; EC 3.6.5.-; Interferon-Induced Guanylate-Binding Protein 2;

NCIt definition : Guanylate-binding protein 2 (591 aa, 67 kDa) is encoded by the human GBP2 gene. This protein is involved in interferon-dependent antimicrobial responses.;

Details

Origin ID

C189210;

UMLS CUI

C2603470;

Automatic exact mappings (from CISMeF team)
- Gtp-binding protein 2 [OMIM gene]
- Guanylate-binding protein 2, interferon-inducible [OMIM gene]
- guanylate binding protein 2 [HGNC gene]
OMIM relation
- Guanylate-binding protein 2, interferon-inducible [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- GBP2 protein, human [MeSH Supplementary Concept]
- GBP2 protein, human [MeSH concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- GBP2 Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytoplasm [NCIt concept]
gene_product_has_biochemical_function
- GTPase [NCIt concept]
gene_product_has_structural_domain_or_motif
- GTP Binding Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- NOD-Like Receptor Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Antimicrobial Effect [NCIt concept]
- GTP Binding [NCIt concept]
- Hydrolysis [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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