Carnitine O-Palmitoyltransferase 1, Liver Isoform

Preferred Label : Carnitine O-Palmitoyltransferase 1, Liver Isoform;

NCIt synonyms : Carnitine O-Palmitoyltransferase I, Liver Isoform; CPT I; Carnitine Palmitoyltransferase IA; CPT IA; EC 2.3.1.21; CPT1A; CPT1-Alpha; CPTI-L; Carnitine Palmitoyltransferase 1A; CPT1-L;

NCIt definition : Carnitine O-palmitoyltransferase 1, liver isoform (773 aa, 88 kDa) is encoded by the human CPT1A gene. This protein is involved in both hepatic triglyceride metabolism and the transfer of the acyl group of long-chain fatty acid-CoA conjugates onto carnitine, which facilitates mitochondrial uptake.;

NCI Metathesaurus CUI : CL1670974;

Détails

Origin ID

C186489;

UMLS CUI

C3530080;

OMIM relation
- Carnitine palmitoyltransferase I, liver [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- CPT1A protein, human [MeSH Supplementary Concept]
- CPT1A protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- CPT1A Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_expressed_in_tissue
- Cardiac Tissue [NCIt concept]
- Hepatic Tissue [NCIt concept]
- Renal Tissue [NCIt concept]
- Skeletal Muscle Tissue [NCIt concept]
gene_product_has_associated_anatomy
- Outer Mitochondrial Membrane [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- Adipocytokine Signaling Pathway [NCIt concept]
- Fatty Acid Metabolism Pathway [NCIt concept]
- PPAR Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Fatty Acid Metabolism [NCIt concept]
- Lipid Transport [NCIt concept]
- Triglyceride Metabolism [NCIt concept]

Position du mot-clé dans l'(les) arborescence(s) :

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