Cytochrome C Oxidase Subunit 1

Preferred Label : Cytochrome C Oxidase Subunit 1;

NCIt synonyms : COX Complex IV Subunit I; MT-CO1; EC 7.1.1.9; COX1; Cytochrome C Oxidase I; Cytochrome C Oxidase Subunit I; Cytochrome C Oxidase Polypeptide I; EC 1.9.3.1, Formerly;

NCIt definition : Cytochrome c oxidase subunit 1 (513 aa, 57 kDa) is encoded by the human MT-CO1 gene. This protein plays a role in the final step of oxidative phosphorylation in the mitochondrion.;

NCIt note : Cytochrome c oxidase subunit 1 is the catalytic subunit of the last enzyme in the mitochondrial electron transport chain, cytochrome c oxidase. Cytochrome c catalyzes the transfer of electrons from reduced cytochrome c to oxygen and yields water. (OMIM);

Details

Origin ID

C128943;

UMLS CUI

C4284184;

Automatic exact mappings (from CISMeF team)
- Complex Iv, cytochrome C oxidase subunit I [OMIM gene]
- Prostaglandin-endoperoxide synthase 1 [OMIM gene]
- cyclooxygenase 1 [MeSH Descriptor]
- mitochondrially encoded cytochrome c oxidase I [ORDO Gene]
OMIM relation
- Complex Iv, cytochrome C oxidase subunit I [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- MT-CO1 Gene [NCIt concept]
- Oxidoreductase Gene [NCIt concept]
- Translocase Gene [NCIt concept]
gene_product_expressed_in_tissue
- All Sites [NCIt concept]
gene_product_has_associated_anatomy
- Electron-Transport Chain of the Respiratory Enzymes [NCIt concept]
- Inner Mitochondrial Membrane [NCIt concept]
- Mitochondrion [NCIt concept]
gene_product_has_biochemical_function
- Protein Complex Subunit [NCIt concept]
gene_product_has_chemical_classification
- Mitochondrial Membrane Protein [NCIt concept]
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- Alzheimer's Disease Pathway KEGG [NCIt concept]
- Cardiac Muscle Contraction Pathway [NCIt concept]
- Huntington's Disease Pathway [NCIt concept]
- Oxidative Phosphorylation Pathway [NCIt concept]
- Parkinson's Disease Pathway KEGG [NCIt concept]
gene_product_is_physical_part_of
- Cytochrome C Oxidase [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Respiration [NCIt concept]
- Nucleotide Metabolic Process [NCIt concept]
- Transport Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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