Guanylate-Binding Protein 1

Preferred Label : Guanylate-Binding Protein 1;

NCIt synonyms : huGBP-1; GTP-Binding Protein 1; Guanine Nucleotide-Binding Protein 1; GBP-1; GBP1; Guanylate Binding Protein 1; EC 3.6.5.-; Interferon-Induced Guanylate-Binding Protein 1;

NCIt definition : Guanylate-binding protein 1 (592 aa, 68 kDa) is encoded by the human GBP1 gene. This protein plays a role in GTPase activity during antimicrobial responses.;

Details

Origin ID

C189205;

UMLS CUI

C1454248;

OMIM relation
- Guanylate-binding protein 1, interferon-inducible, 67-kd [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- GBP1 protein, human [MeSH Supplementary Concept]
- GBP1 protein, human [MeSH concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- GBP1 Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
gene_product_has_biochemical_function
- GTPase [NCIt concept]
gene_product_has_structural_domain_or_motif
- GTP Binding Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- NOD-Like Receptor Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Antimicrobial Effect [NCIt concept]
- GTP Binding [NCIt concept]
- Hydrolysis [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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