NCIt definition : Glutamate decarboxylase 1 (594 aa, 67 kDa) is encoded by the human GAD1 gene. This
protein is involved in the conversion of glutamate to gamma-aminobutyric acid.;
Alternative definition : CDISC: An antigen of the 67 kDa isoform of GAD which is encoded by the GAD1 gene.
It can be considered as an autoantigen and is commonly associated with the autoimmune
disease type 1 diabetes.;