Xanthine Dehydrogenase/Oxidase

Preferred Label : Xanthine Dehydrogenase/Oxidase;

NCIt synonyms : XDH; EC 1.1.1.204; Xanthine Oxidoreductase; Xanthine Oxidase; EC 1.1.3.22; XO; XOR; Xanthine Dehydrogenase; XD;

NCIt definition : Xanthine dehydrogenase/oxidase (1333 aa, 146 kDa) is encoded by the human XDH gene. This protein is involved in purine degradation.;

NCIt note : Homodimers of xanthine dehydrogenase/oxidase have both xanthine dehydrogenase (XD) activity (EC 1.17.1.4) and xanthine oxidase (XO, xanthine oxidoreductase, XOR) activity (EC 1.17.3.2). (UniProt);

Details

Origin ID

C39587;

UMLS CUI

C5441738;

Currated CISMeF NLP mapping
- Xanthine dehydrogenase (substance) [SNOMED CT concept]
- Xanthine oxidase (substance) [SNOMED CT concept]
- xanthine dehydrogenase [SNOMED Notion]
- xanthine oxidase [MeSH Descriptor]
- xanthine oxidase [MeSH concept]
- xanthine oxidase [SNOMED Notion]
OMIM relation
- Xanthine dehydrogenase [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Xanthine dehydrogenase (substance) [SNOMED CT concept]
- xanthine dehydrogenase [SNOMED Notion]
- xanthine dehydrogenase [MeSH concept]
- xanthine dehydrogenase [MeSH Descriptor]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Oxidoreductase Gene [NCIt concept]
- XDH Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytosol [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Caffeine Metabolism Pathway [NCIt concept]
- Drug Metabolism by Non-CYP450 Enzymes Pathway [NCIt concept]
- Peroxisome Biogenesis Pathway [NCIt concept]
- Purine Metabolism Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Negative Regulation of Angiogenesis [NCIt concept]
- Nucleotide Metabolic Process [NCIt concept]
- Oxidation [NCIt concept]
- Oxidation/Reduction [NCIt concept]
- Signal Transduction Inhibition [NCIt concept]
is_target
- Allopurinol [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients