" /> E3 Ubiquitin-Protein Ligase Makorin-1 - CISMeF





Preferred Label : E3 Ubiquitin-Protein Ligase Makorin-1;

NCIt synonyms : Makorin Ring Finger Protein 1; EC 6.3.2.-, Formerly; Makorin 1; RING Finger Protein 61; Makorin-1; EC 2.3.2.27;

NCIt definition : E3 ubiquitin-protein ligase makorin-1 (482 aa, 53 kDa) is encoded by the human MKRN1 gene. This protein is involved in the ubiquitination of proteins that regulate both cell survival and gene expression.;

NCIt note : Substrates for E3 ubiquitin-protein ligase makorin-1 include FILIP1, p53/TP53, CDKN1A and TERT. (UniProt);

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29/07/2025


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