Double-Stranded RNA-Specific Adenosine Deaminase

Preferred Label : Double-Stranded RNA-Specific Adenosine Deaminase;

NCIt synonyms : Interferon-Induced Protein 4; DRADA; IFI-4; EC 3.5.4.37; ADAR; 136 kDa Double-Stranded RNA-Binding Protein; Interferon-Inducible Protein 4; p136; K88DSRBP; dsRNA Adenosine Deaminase; RNA-Specific Adenosine Deaminase;

NCIt definition : Double-stranded RNA-specific adenosine deaminase (1226 aa, 136 kDa) is encoded by the human ADAR gene. This protein plays a role in the deamination of adenosine to inosine in double-stranded RNA (A-to-I RNA editing).;

NCI Metathesaurus CUI : CL937010;

Details

Origin ID

C157285;

UMLS CUI

C4761503;

Automatic exact mappings (from CISMeF team)
- 2'-5'-oligoadenylate synthetase 1 [ORDO Gene]
- Adenosine deaminase, rna-specific [OMIM gene]
- adenosine deaminase RNA specific [ORDO Gene]
- adenosine deaminase RNA specific [HGNC gene]
- double-stranded RNA-specific adenosine deaminase [OBI concept]
OMIM relation
- Adenosine deaminase, rna-specific [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
gene_encodes_gene_product
- ADAR Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
gene_product_has_biochemical_function
- RNA Binding Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Double-Stranded RNA Binding Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Cytosolic DNA-Sensing Pathway [NCIt concept]
- RNA Polymerase III Transcription Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Hydrolysis [NCIt concept]
- Immune Response Process [NCIt concept]
- Nucleotide Metabolic Process [NCIt concept]
- RNA Binding [NCIt concept]
- RNA Interference [NCIt concept]
- RNA Processing [NCIt concept]

Keyword's position in hierarchy(ies) :

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