Protein Arginine N-Methyltransferase 1

Preferred Label : Protein Arginine N-Methyltransferase 1;

NCIt synonyms : Interferon Receptor 1-Bound Protein 4; Histone-Arginine N-Methyltransferase PRMT1; EC 2.1.1.319; Heterogeneous Nuclear Ribonucleoprotein Methyltransferase 1-Like 2; PRMT1;

NCIt definition : Protein arginine N-methyltransferase 1 (361 aa, 42 kDa) is encoded by the human PRMT1 gene. This protein plays a role in the methylation of the guanidino nitrogens of arginyl residues in substrate proteins.;

NCI Metathesaurus CUI : CL522226;

Details

Origin ID

C134687;

UMLS CUI

C4522248;

Automatic exact mappings (from CISMeF team)
- Protein arginine methyltransferase 1 [OMIM gene]
- Protein-Arginine N-Methyltransferases [MeSH Descriptor]
OMIM relation
- Protein arginine methyltransferase 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Methyltransferase Gene [NCIt concept]
- PRMT1 Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytoplasm [NCIt concept]
- Nucleus [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- BTG Cell Cycle Regulation Pathway [NCIt concept]
- Gene Expression Regulation by Vitamin D Receptor Pathway [NCIt concept]
- p53 Effector Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Chromatin Remodeling [NCIt concept]
- Methylation [NCIt concept]
- Protein Methylation [NCIt concept]
is_target
- PRMT1 Inhibitor GSK3368715 [NCIt concept]

Keyword's position in hierarchy(ies) :

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