Aspartyl/Asparaginyl Beta-Hydroxylase

Preferred Label : Aspartyl/Asparaginyl Beta-Hydroxylase;

NCIt synonyms : Aspartate Beta-Hydroxylase; Peptide-Aspartate Beta-Dioxygenase; Asparagine Hydroxylase; ASPH Isoform 1; EC 1.14.11.16; Aspartyl/Asparaginyl-Beta-Hydroxylase; ASP Beta-Hydroxylase; HAAH; AAH; BAH; ASPH;

NCIt definition : Aspartyl/asparaginyl beta-hydroxylase (758 aa, 86 kDa) is encoded by the human ASPH gene. This protein is involved in amino acid hydroxylation.;

NCIt note : Aspartyl/asparaginyl beta-hydroxylase is encoded by exons 1, 3, 5, and 8 through 16 of the ASPH gene. (OMIM);

NCI Metathesaurus CUI : CL976717;

Details

Origin ID

C163041;

UMLS CUI

C5235417;

Automatic exact mappings (from CISMeF team)
- Aspartate beta-hydroxylase [OMIM gene]
- aspartate beta-hydroxylase [ORDO Gene]
- aspartate beta-hydroxylase [HGNC gene]
- heme [MeSH Descriptor]
- hypoxia inducible factor 1 subunit alpha inhibitor [HGNC gene]
Currated CISMeF NLP mapping
- Peptide-aspartate beta-dioxygenase (substance) [SNOMED CT concept]
- aspartic acid 2-oxoglutarate-dependent dioxygenase [MeSH Supplementary Concept]
- aspartic acid 2-oxoglutarate-dependent dioxygenase [MeSH concept]
OMIM relation
- Aspartate beta-hydroxylase [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- ASPH Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Oxidoreductase Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
gene_product_has_associated_anatomy
- Membrane of the Endoplasmic Reticulum [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
- Tetratricopeptide Repeat [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- Hypoxia-Inducible Factor Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Hydroxylation [NCIt concept]
- Oxidation [NCIt concept]
- Oxidation/Reduction [NCIt concept]
- Post-Translational Modification [NCIt concept]
is_target
- HAAH Lambda phage Vaccine SNS-301 [NCIt concept]

Keyword's position in hierarchy(ies) :

Main resources

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