Dolichyl-Diphosphooligosaccharide-Protein Glycosyltransferase Subunit DAD1

Preferred Label : Dolichyl-Diphosphooligosaccharide-Protein Glycosyltransferase Subunit DAD1;

NCIt synonyms : Oligosaccharyl Transferase Subunit DAD1; EC 2.4.99.18; Defender Against Cell Death 1; DAD1; Dolichyl-Diphosphooligosaccharide--Protein Glycosyltransferase Subunit DAD1; DAD-1;

NCIt definition : Dolichyl-diphosphooligosaccharide-protein glycosyltransferase subunit DAD1 (113 aa, 12 kDa) is encoded by the human DAD1 gene. This protein plays a role in the addition of high-mannose oligosaccharides to asparagine residues.;

NCIt note : Dolichyl-diphosphooligosaccharide-protein glycosyltransferase subunit DAD1 catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent proteins. (UniProt);

Details

Origin ID

C105734;

UMLS CUI

C0220374;

Automatic exact mappings (from CISMeF team)
- Defender against cell death 1 [OMIM gene]
- defender against cell death 1 [HGNC gene]
OMIM relation
- Defender against cell death 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- DAD1 protein, human [MeSH Supplementary Concept]
- DAD1 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- DAD1 Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Glycosyltransferase Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Membrane of the Endoplasmic Reticulum [NCIt concept]
gene_product_has_chemical_classification
- Protein Complex Subunit [NCIt concept]
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- N-Glycan Biosynthesis Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Carbohydrate Metabolic Process [NCIt concept]
- Glycosylation [NCIt concept]
- Negative Regulation of Cell Death [NCIt concept]
- Protein Glycosylation [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients