Double-Stranded RNA-Specific Editase B2

Preferred Label : Double-Stranded RNA-Specific Editase B2;

NCIt synonyms : EC 3.5.-.-; RNA-Dependent Adenosine Deaminase 3; RNA-Editing Enzyme 2; RNA-Editing Deaminase 2; ADARB2; dsRNA Adenosine Deaminase B2;

NCIt definition : Double-stranded RNA-specific editase B2 (739 aa, 81 kDa) is encoded by the human ADARB2 gene. This protein plays a role in RNA binding and editing.;

NCIt note : Double-stranded RNA-specific editase B2 does not appear to have RNA editing activity; it likely binds to RNA substrates, which sterically hinders the activity of other RNA editases. (UniProt);

NCI Metathesaurus CUI : CL964001;

Details

Origin ID

C206189;

OMIM relation
- Adenosine deaminase, rna-specific, b2 [OMIM gene]
gene_encodes_gene_product
- ADARB2 Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytoplasm [NCIt concept]
- Nucleolus [NCIt concept]
gene_product_has_biochemical_function
- RNA Binding Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Double-Stranded RNA Binding Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Hydrolysis [NCIt concept]
- Nucleotide Metabolic Process [NCIt concept]
- RNA Binding [NCIt concept]
- RNA Processing [NCIt concept]

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