Cystathionine Gamma-Lyase

Preferred Label : Cystathionine Gamma-Lyase;

NCIt synonyms : Homocysteine Desulfhydrase; CSE; CTH; EC 4.4.1.1; EC 4.4.1.2; Cysteine-Protein Sulfhydrase; Gamma-Cystathionase; CGL; Cysteine Desulfhydrase;

NCIt definition : Cystathionine gamma-lyase (405 aa, 45 kDa) is encoded by the human CTH gene. This protein is involved in the last step in the trans-sulfuration pathway from L-methionine to L-cysteine.;

NCI Metathesaurus CUI : CL1907109;

Details

Origin ID

C200290;

OMIM relation
- Cystathionine gamma-lyase [OMIM gene]
gene_encodes_gene_product
- CTH Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Lyase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytosol [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Cysteine and Methionine Metabolism Pathway [NCIt concept]
- Glycine, Serine and Threonine Metabolism Pathway [NCIt concept]
- Selenoamino Acid Metabolism Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Amino Acid Biosynthesis [NCIt concept]

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