1-Phosphatidylinositol 4,5-Bisphosphate Phosphodiesterase Beta-4

Preferred Label : 1-Phosphatidylinositol 4,5-Bisphosphate Phosphodiesterase Beta-4;

NCIt synonyms : EC 3.1.4.11; 1-Phosphatidylinositol-4,5-Bisphosphate Phosphodiesterase Beta 4; PLCB4; PLC-Beta-4; 1-Phosphatidylinositol 4,5-Bisphosphate Phosphodiesterase Beta 4; Phospholipase C Beta 4; Phospholipase C-Beta-4; Phosphoinositide Phospholipase C-Beta-4;

NCIt definition : 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 (1175 aa, 134 kDa) is encoded by the human PLCB4 gene. This protein is involved in the synthesis of diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3).;

Details

Origin ID

C160886;

UMLS CUI

C5202928;

Automatic exact mappings (from CISMeF team)
- Phospholipase C, beta-4 [OMIM gene]
- phospholipase C beta 4 [ORDO Gene]
- phospholipase C beta 4 [HGNC gene]
- phospholipase c beta [MeSH Descriptor]
OMIM relation
- Phospholipase C, beta-4 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Esterase Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- PLCB4 Gene [NCIt concept]
gene_product_has_biochemical_function
- Hydrolase [NCIt concept]
gene_product_has_structural_domain_or_motif
- C2 Domain [NCIt concept]
- EF-Hand Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Alzheimer's Disease Pathway KEGG [NCIt concept]
- Amoebiasis Pathway [NCIt concept]
- Calcium-Mediated Signaling Pathway [NCIt concept]
- Chagas Disease Pathway [NCIt concept]
- Chemokine Signaling Pathway [NCIt concept]
- Gap Junction Assembly Pathway [NCIt concept]
- Gastric Acid Secretion Pathway [NCIt concept]
- Gonadotropin-Releasing Hormone Signaling Pathway [NCIt concept]
- Huntington's Disease Pathway [NCIt concept]
- Inositol Phosphate Metabolism Pathway [NCIt concept]
- Long-Term Depression Pathway [NCIt concept]
- Long-Term Potentiation Pathway [NCIt concept]
- Lysophosphatidic Acid Receptor Signaling Pathway [NCIt concept]
- Melanogenesis Pathway [NCIt concept]
- NOD-Like Receptor Signaling Pathway [NCIt concept]
- Phosphatidylinositol Signaling System Pathway [NCIt concept]
- Salivary Secretion Pathway [NCIt concept]
- Vascular Smooth Muscle Contraction Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Hydrolysis [NCIt concept]
- Lipid Metabolic Process [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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