Matrix Metalloproteinase-16

Preferred Label : Matrix Metalloproteinase-16;

NCIt synonyms : Membrane-Type Matrix Metalloproteinase 3; Membrane-Type-3 Matrix Metalloproteinase; MT3MMP; Matrix Metalloprotease 16; MT3-MMP; Matrix Metalloprotease-16; MMP-X2; EC 3.4.24.-; MT-MMP 3; MMP-16; Putative Transmembrane Protein C8orf57; MTMMP3; Matrix Metalloproteinase 16; MMP16;

NCIt definition : Matrix metalloproteinase-16 (607 aa, 70 kDa) is encoded by the human MMP16 gene. This protein plays a role in endoproteolysis that mediates 72 kDa type IV collagenase activation and extracellular matrix remodeling.;

Details

Origin ID

C122075;

UMLS CUI

C1568288;

Automatic exact mappings (from CISMeF team)
- Matrix metalloproteinase 16 [OMIM gene]
- matrix metalloproteinase 16 [MeSH concept]
- matrix metalloproteinase 16 [MeSH Descriptor]
OMIM relation
- Matrix metalloproteinase 16 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- MMP16 protein, human [MeSH Supplementary Concept]
- MMP16 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- MMP16 Gene [NCIt concept]
- Metallopeptidase Gene [NCIt concept]
- Peptidase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_chemical_classification
- Metalloprotein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Protease Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_biomarker_type
- Metastasis and Aggressiveness Marker [NCIt concept]
gene_product_plays_role_in_biological_process
- Hydrolysis [NCIt concept]
- Metal Ion Binding [NCIt concept]
- Proteolysis [NCIt concept]

Keyword's position in hierarchy(ies) :

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