MeSH definition : A transmembrane domain-containing matrix metalloproteinase. It is synthesized as an
inactive zymogen that is activated by the proteolytic action of PROPROTEIN CONVERTASES.
Matrix metalloproteinase 16 plays a direct role in the cleavage of proteins in the
pericellular environment. In addition, it can function indirectly by enzymatically
activating the proprotein form of other MATRIX METALLOPROTEINASES such as the zymogen
of MATRIX METALLOPROTEINASE 2.;
A transmembrane domain-containing matrix metalloproteinase. It is synthesized as an
inactive zymogen that is activated by the proteolytic action of PROPROTEIN CONVERTASES.
Matrix metalloproteinase 16 plays a direct role in the cleavage of proteins in the
pericellular environment. In addition, it can function indirectly by enzymatically
activating the proprotein form of other MATRIX METALLOPROTEINASES such as the zymogen
of MATRIX METALLOPROTEINASE 2.