Delta-1-Pyrroline-5-Carboxylate Dehydrogenase, Mitochondrial

Preferred Label : Delta-1-Pyrroline-5-Carboxylate Dehydrogenase, Mitochondrial;

NCIt synonyms : P5C Dehydrogenase; ALDH4A1; Mitochondrial Delta-1-Pyrroline 5-Carboxylate Dehydrogenase; EC 1.2.1.88; Aldehyde Dehydrogenase Family 4 Member A1; L-Glutamate Gamma-Semialdehyde Dehydrogenase; Aldehyde Dehydrogenase 4 Family Member A1; Pyrroline-5-Carboxylate Dehydrogenase; Aldehyde Dehydrogenase 4;

NCIt definition : Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial (563 aa, 62 kDa) is encoded by the human ALDH4A1 gene. This protein is involved in the conversion of proline pyrroline-5-carboxylate to glutamate.;

NCI Metathesaurus CUI : CL553380;

Details

Origin ID

C152045;

UMLS CUI

C4724712;

Automatic exact mappings (from CISMeF team)
- Aldehyde dehydrogenase, family 4, subfamily a, member 1 [OMIM gene]
- aldehyde dehydrogenase 4 family member A1 [ORDO Gene]
- aldehyde dehydrogenase 4 family member A1 [HGNC gene]
OMIM relation
- Aldehyde dehydrogenase, family 4, subfamily a, member 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
gene_encodes_gene_product
- ALDH4A1 Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Oxidoreductase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Mitochondrial Matrix [NCIt concept]
gene_product_has_biochemical_function
- Aldehyde Dehydrogenase [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Alanine, Aspartate and Glutamate Metabolism Pathway [NCIt concept]
- Arginine and Proline Metabolism Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Intermediary Metabolic Process [NCIt concept]
- Oxidation [NCIt concept]
- Oxidation/Reduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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