Histone-Lysine N-Methyltransferase PRDM16

Preferred Label : Histone-Lysine N-Methyltransferase PRDM16;

NCIt synonyms : PR Domain-Containing Protein 16; MDS1/EVI1-Like 1; PRDM16; Transcription factor MEL1; PR Domain Containing Protein 16;

NCIt related terms : PR Domain Zinc Finger Protein 16;

NCIt definition : Histone-lysine N-methyltransferase PRDM16 (1276 aa, 140 kDa) is encoded by the human PRDM16 gene. This protein plays a role in both transcriptional regulation and fat cell differentiation.;

Details

Origin ID

C97738;

UMLS CUI

C3273600;

OMIM relation
- Pr domain-containing protein 16 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- PRDM16 protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Methyltransferase Gene [NCIt concept]
- PRDM16 Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
- Transcription Factor Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_expressed_in_tissue
- Kidney [NCIt concept]
- Uterus [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- DNA Binding Protein [NCIt concept]
- Sequence-Specific DNA Binding Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- C2H2 Zinc Finger [NCIt concept]
- SET Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Differentiation Process [NCIt concept]
- Cell Respiration [NCIt concept]
- DNA Binding [NCIt concept]
- Histone Methylation [NCIt concept]
- Methylation [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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