Inosine-5'-Monophosphate Dehydrogenase 1

Preferred Label : Inosine-5'-Monophosphate Dehydrogenase 1;

NCIt synonyms : IMPDH 1; EC 1.1.1.205; IMPD 1; IMPDH-I; IMP Dehydrogenase 1; IMP-Dehydrogenase-1; IMPDH1;

NCIt definition : Inosine-5'-monophosphate dehydrogenase 1 (514 aa, 55 kDa) is encoded by the human IMPDH1 gene. This protein plays a role in guanine nucleotide biosynthesis.;

Details

Origin ID

C38923;

UMLS CUI

C1454821;

OMIM relation
- Imp dehydrogenase 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- IMPDH1 protein, human [MeSH concept]
- IMPDH1 protein, human [MeSH Supplementary Concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- IMPDH1 Gene [NCIt concept]
- Oxidoreductase Gene [NCIt concept]
gene_product_affected_by_chemical_or_drug
- Tiazofurin [NCIt concept]
gene_product_has_associated_anatomy
- Cytosol [NCIt concept]
- Nucleus [NCIt concept]
gene_product_has_chemical_classification
- Inosine Monophosphate Dehydrogenase [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Drug Metabolism by Non-CYP450 Enzymes Pathway [NCIt concept]
- Purine Metabolism Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Nucleotide Metabolic Process [NCIt concept]
- Oxidation [NCIt concept]
- Oxidation/Reduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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