Proteasome Subunit Beta Type-8

Preferred Label : Proteasome Subunit Beta Type-8;

NCIt synonyms : Proteasome Subunit Beta-5i; Low Molecular Weight Protein 7; Really Interesting New Gene 10 Protein; Large Multifunctional Protease 7; Protease Component C13; Macropain Subunit C13; Large Multifunctional Peptidase 7; Proteasome Component C13; EC 3.4.25.1; Proteasome Subunit Y2; Proteasome Subunit Beta 5i; Multicatalytic Endopeptidase Complex Subunit C13; Low Molecular Mass Protein 7; PSMB8;

NCIt definition : Proteasome subunit beta type-8 (276 aa, 30 kDa) is encoded by the human PSMB8 gene. This protein plays a role in both protein metabolism and the generation of MHC class I-binding peptides.;

Details

Origin ID

C112077;

UMLS CUI

C1527848;

Automatic exact mappings (from CISMeF team)
- Proteasome subunit, beta-type, 8 [OMIM gene]
- proteasome 20S subunit beta 8 [ORDO Gene]
OMIM relation
- Proteasome subunit, beta-type, 8 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- PSMB8 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- PSMB8 Gene [NCIt concept]
- Peptidase Gene [NCIt concept]
gene_product_expressed_in_tissue
- Dendritic Cell [NCIt concept]
gene_product_has_associated_anatomy
- Proteasome [NCIt concept]
gene_product_has_structural_domain_or_motif
- Protease Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Proteasome Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Antigen Processing [NCIt concept]
- Hydrolysis [NCIt concept]
- Proteolytic Processing [NCIt concept]
- Ubiquitinated Protein Degradation [NCIt concept]
is_target
- LMP7 Inhibitor M3258 [NCIt concept]

Keyword's position in hierarchy(ies) :

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