Neutrophil Collagenase

Preferred Label : Neutrophil Collagenase;

NCIt synonyms : PMNL-CL; Human Collagenase 2; CLG1; HNC; MMP8; PMNL Collagenase; Matrix Metalloprotease-8; Matrix Metalloproteinase-8; Matrix Metalloprotease 8; Matrix Metalloproteinase 8; EC 3.4.24.34;

NCIt definition : Neutrophil collagenase (467 aa, 53 kDa) is encoded by the human MMP8 gene. This protein plays a role in the proteolysis of fibrillar collagen.;

Details

Origin ID

C41046;

UMLS CUI

C1721358;

Currated CISMeF NLP mapping
- Neutrophil collagenase (substance) [SNOMED CT concept]
- matrix metalloproteinase 8 [MeSH Descriptor]
- matrix metalloproteinase 8 [MeSH concept]
OMIM relation
- Matrix metalloproteinase 8 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- MMP8 protein, human [MeSH concept]
- MMP8 protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- MMP8 Gene [NCIt concept]
- Metallopeptidase Gene [NCIt concept]
- Peptidase Gene [NCIt concept]
gene_product_affected_by_chemical_or_drug
- Rebimastat [NCIt concept]
gene_product_has_biochemical_function
- Collagenase [NCIt concept]
gene_product_has_chemical_classification
- Metalloprotein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Protease Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
gene_product_is_biomarker_type
- Metastasis and Aggressiveness Marker [NCIt concept]
gene_product_plays_role_in_biological_process
- Hydrolysis [NCIt concept]
- Metal Ion Binding [NCIt concept]
- Proteolysis [NCIt concept]
is_target
- Rebimastat [NCIt concept]

Keyword's position in hierarchy(ies) :

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