E3 Ubiquitin-Protein Ligase RNF139

Preferred Label : E3 Ubiquitin-Protein Ligase RNF139;

NCIt synonyms : RNF139; TRC8; Ring Finger 139; Patched Related Protein TRC8; Translocation In Renal Carcinoma On Chromosome 8 Protein; Multiple Membrane Spanning Receptor-TRC8; Multiple Membrane Spanning Receptor TRC8; EC 6.3.2.-, Formerly; EC 2.3.2.27;

NCIt definition : E3 ubiquitin-protein ligase RNF139 (664 aa, 76 kDa) is encoded by the human RNF139 gene. This protein plays a role in protein ubiquitination, inhibition of cell proliferation and cell cycle regulation.;

Details

Origin ID

C30127;

UMLS CUI

C0756527;

OMIM relation
- Ring finger protein 139 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- RNF139 protein, human [MeSH concept]
- RNF139 protein, human [MeSH Supplementary Concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- RNF139 Gene [NCIt concept]
- Transferase Gene [NCIt concept]
- Ubiquitin-Transferase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Endoplasmic Reticulum [NCIt concept]
gene_product_has_biochemical_function
- Ubiquitination Regulation Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ring Finger Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
gene_product_is_physical_part_of
- Ubiquitin Protein Ligase [NCIt concept]
gene_product_plays_role_in_biological_process
- Inhibition of Cell Proliferation [NCIt concept]
- Translational Repression [NCIt concept]
- Ubiquitinated Protein Degradation [NCIt concept]
- Ubiquitination [NCIt concept]

Keyword's position in hierarchy(ies) :

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