Methylthioribulose-1-Phosphate Dehydratase

Preferred Label : Methylthioribulose-1-Phosphate Dehydratase;

NCIt synonyms : APAF1 Interacting Protein; MTRu-1-P Dehydratase; APIP; hAPIP; Probable Methylthioribulose-1-Phosphate Dehydratase; APAF1-Interacting Protein; EC 4.2.1.109;

NCIt definition : Methylthioribulose-1-phosphate dehydratase (242 aa, 27 kDa) is encoded by the human APIP gene. This protein is involved in the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) for methionine salvage.;

Details

Origin ID

C186723;

UMLS CUI

C3493576;

Automatic exact mappings (from CISMeF team)
- APAF1 interacting protein [HGNC gene]
- Apaf1-interacting protein [OMIM gene]
OMIM relation
- Apaf1-interacting protein [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- APIP protein, human [MeSH Supplementary Concept]
- APIP protein, human [MeSH concept]
gene_encodes_gene_product
- APIP Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Lyase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytosol [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Cysteine and Methionine Metabolism Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Amino Acid Biosynthesis [NCIt concept]

Keyword's position in hierarchy(ies) :

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