Alpha-Aminoadipic Semialdehyde Synthase, Mitochondrial

Preferred Label : Alpha-Aminoadipic Semialdehyde Synthase, Mitochondrial;

NCIt synonyms : Lysine Ketoglutarate Reductase/Saccharopine Dehydrogenase; LKR/SDH; Alpha-Aminoadipic Semialdehyde Synthase; AASS; Lysine-Ketoglutarate Reductase/Saccharopine Dehydrogenase; Alpha-Aminoadipate Semialdehyde Synthase; Aminoadipate-Semialdehyde Synthase;

NCIt definition : Alpha-aminoadipic semialdehyde synthase, mitochondrial (926 aa, 102 kDa) is encoded by the human AASS gene. This protein plays a role in the two step conversion of lysine to alpha-aminoadipic semialdehyde.;

NCIt note : Alpha-aminoadipic semialdehyde synthase, mitochondrial has both lysine ketoglutarate reductase (EC 1.5.1.8) and saccharopine dehydrogenase (EC 1.5.1.9) activity. (UniProt);

Details

Origin ID

C191888;

UMLS CUI

C1306959;

OMIM relation
- Alpha-aminoadipic semialdehyde synthase [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- AASS protein, human [MeSH Supplementary Concept]
- AASS protein, human [MeSH concept]
gene_encodes_gene_product
- AASS Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Oxidoreductase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Mitochondrial Matrix [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Lysine Degradation Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Catabolic Process [NCIt concept]
- Oxidation [NCIt concept]
- Oxidation/Reduction [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients